Part Used : ไม่ระบุ
Activity : P-GLYCOPROTEIN INHIBITION
Solvent/Active Compound : Alopecurone (ALOB)
Type of experiment : -
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : -
Dose/Conc.(herb) : 10 micromolar
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : -
Dose/Conc.(drug) : -
Remark : Mg-63 and MG-63/DOX cells were incubated with 10 micromolar ALOB for 0-48 hours. The expression of P-glycoprotein at membrane surface was analyzed by flow cytometry.
Note : The human osteosarcoma cell line (MG-63)
A DOX resistance cell line (MG-63/DOX)