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Part Used : ยาง

Activity : CYP1A2 INDUCTION

Solvent/Active Compound : ethyl acetate and methanol

Type of experiment : in vivo

Type of animal : rat

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : Oral administration

Dose/Conc.(herb) : 1,428 mg/kg/day

Duration : 3 days

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Negative

Remark : Administration of CMGE at the recommended pharmaceutical dose does not induce significant transcriptional modulation of Cyp1a1/2 and subsequent enzyme activity induction of CYP1A1.

Note : CMGE= Chios mastic gum extract

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