Part Used : ไม่ระบุ
Activity : CYP3A4 INDUCTION
Solvent/Active Compound : Cynaramin*
Type of experiment : in vitro
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : -
Dose/Conc.(herb) : 100 microgram/ml
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : -
Dose/Conc.(drug) : -
Remark : *Cynaramin comprised of Taraxacum officinale, Peumus boldus, Cynara scolymus and Mentha piperita
- Cynaramin caused 5.4+/-09 fold-induction of MDR1 mRNA expression. However it could not significantly induced mRNA expression of CYP1A2 and CYP3A4.