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Part Used : ไม่ระบุActivity : ANTIHYPERGLYCEMIC ACTIVITYSolvent/Active Compound : saponinsType of experiment : humanType of animal : -Type of study : Double-blind trialN(Total) : 69 (M/F = 38/31)N(Treatment) : 46 (M/F = 25/21)Sex : Both sexAge : 54.8 +/-7.2 years (control = 53.7 +/-6.8 years)Route : Oral administrationDose/Conc.(herb) : 6 capsules each time and thrice a day after mealsDuration : 12 weeksType of interaction : PharmacodynamicsInteraction with drug : SulfonylureaDose/Conc.(drug) : -Result : PositiveRemark : Results: The combined therapy of TFGs with sulfonylureas hypoglycemic drug could lower the blood glucose level and ameliorate clinical symptoms in the treatment of T2DM, and the therapy was relatively safe.Note : Subject total: patients with type 2 diabetes mellitus (T2DM) not well controlled by sulfonylureas alone were randomly assigned to the treated group (46 cases) and the control group (23 cases). Dose: Trigonella foenum-graecum L. total saponins (TFGs) capsules; 0.35 g/pill, each gram of powder equals to 16 g of crude drug.
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : saponinsType of experiment : humanType of animal : -Type of study : Double-blind trialN(Total) : 69 (M/F = 38/31)N(Treatment) : 46 (M/F = 25/21)Sex : Both sexAge : 54.8 +/-7.2 years (control = 53.7 +/-6.8 years)Route : Oral administrationDose/Conc.(herb) : 6 capsules each time and thrice a day after mealsDuration : 12 weeksType of interaction : PharmacodynamicsInteraction with drug : SulfonylureaDose/Conc.(drug) : -Result : PositiveRemark : Results: The combined therapy of TFGs with sulfonylureas hypoglycemic drug could lower the blood glucose level and ameliorate clinical symptoms in the treatment of T2DM, and the therapy was relatively safe.Note : Subject total: patients with type 2 diabetes mellitus (T2DM) not well controlled by sulfonylureas alone were randomly assigned to the treated group (46 cases) and the control group (23 cases). Dose: Trigonella foenum-graecum L. total saponins (TFGs) capsules; 0.35 g/pill, each gram of powder equals to 16 g of crude drug.
Part Used : ไม่ระบุActivity : DIABETES-INHIBITION OF DEVELOPMENTSolvent/Active Compound : saponinsType of experiment : humanType of animal : -Type of study : Double-blind trialN(Total) : 69 (M/F = 38/31)N(Treatment) : 46 (M/F = 25/21)Sex : Both sexAge : 54.8 +/-7.2 years (control = 53.7 +/-6.8 years)Route : Oral administrationDose/Conc.(herb) : 6 capsules each time and thrice a day after mealsDuration : 12 weeksType of interaction : PharmacodynamicsInteraction with drug : SulfonylureaDose/Conc.(drug) : -Result : PositiveRemark : Results: The combined therapy of TFGs with sulfonylureas hypoglycemic drug could lower the blood glucose level and ameliorate clinical symptoms in the treatment of T2DM, and the therapy was relatively safe.Note : Subject total: patients with type 2 diabetes mellitus (T2DM) not well controlled by sulfonylureas alone were randomly assigned to the treated group (46 cases) and the control group (23 cases). Dose: Trigonella foenum-graecum L. total saponins (TFGs) capsules; 0.35 g/pill, each gram of powder equals to 16 g of crude drug.