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Part Used : ดอกActivity : CYP3A1 INHIBITIONSolvent/Active Compound : waterType of experiment : in vitroType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.35 g/kg twice a dayDuration : 5 daysType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : The CYP3A1 mRNA levels were statistically decreased by both doses of Danggui (0.35 and 0.7 g/kg) and Honghua (only 0.7 g/kg) treatments.
Part Used : ดอกActivity : CYP3A1 INHIBITIONSolvent/Active Compound : waterType of experiment : in vitroType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.7 g/kg twice a dayDuration : 5 daysType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : The CYP3A1 mRNA levels were statistically decreased by both doses of Danggui (0.35 and 0.7 g/kg) and Honghua (only 0.7 g/kg) treatments.