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COMPOSITAE (ASTERACEAE) Carthamus tinctorius L.

Synonym

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Thai / English name

คำฝอย*

[1-1] of 1 article(s) found

หน้า 1

[1] EFFECT OF DANGGUI AND HONGHUA ON CYTOCHROME P450 1A2, 2C11, 2E1 AND 3A1 MRNA EXPRESSION IN LIVER OF RATS.
LI Y-H,ZHANG Y-Q,LI L,ET AL.
AM J CHIN MED 2008 Vol.36(6),1071-81 $28629 [Full]

Part Used : ดอก
Activity : CYP2E1 INHIBITION

Solvent/Active Compound : water

Type of experiment : in vitro
Type of animal : rat

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : Oral administration
Dose/Conc.(herb) : 0.35 g/kg twice a day

Duration : 5 days
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : For CYP2E1, the action of 0.35 g/kg Danggui treatment on mRNA levels was moderate, while the other three treatments (0.7 g/kg Danggui, 0.35 and 0.7 g/kg Honghua) provoked strong decreases.

Part Used : ดอก
Activity : CYP2E1 INHIBITION

Solvent/Active Compound : water

Type of experiment : in vitro
Type of animal : rat

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : Oral administration
Dose/Conc.(herb) : 0.7 g/kg twice a day

Duration : 5 days
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : For CYP2E1, the action of 0.35 g/kg Danggui treatment on mRNA levels was moderate, while the other three treatments (0.7 g/kg Danggui, 0.35 and 0.7 g/kg Honghua) provoked strong decreases.

หน้า 1

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