Part Used : ไม่ระบุ
Activity : CYTOCHROME P-450 INHIBITION
Solvent/Active Compound : alcoholic extract of Phyllanthus amarus
Type of experiment : in vivo
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : Oral administration
Dose/Conc.(herb) : 250 mg/kg body weight
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : Phenobarbitone*/Phenobarbital
Dose/Conc.(drug) : -
Remark : Oral administration of the extract was also found to reduce the elevated P450 enzyme activities produced by phenobarbitone by 50% at 250 mg/kg body weight.