Part Used : เปลือกต้น
Activity : ANTIBACTERIAL ACTIVITY
Solvent/Active Compound : Essential oil
Type of experiment : in vitro
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : -
Dose/Conc.(herb) : 25 microlitre
Duration : 20 hours
Type of interaction : Pharmacodynamics
Interaction with drug : Piperacillin
Dose/Conc.(drug) : 25 microlitre
Remark : - MIC of one sample alone for piperacillin (microgram/ml) = 1024, for cinnamon bark (%, v/v) = 0.078
- MIC of one sample of the most effective combination for piperacillin (microgram/ml) = 256, for cinnamon bark (%, v/v) = 0.020
- FIC of antibiotic = 0.25
- FIC of oil = 0.25
- FICI = 0.5
Note : The miniumum inhibitory concentration (MIC) values of the bacterial strains under study were determined by means or broth microdilution as stated in CLSI M07-A8.
FIC = fraction inhibitory concentration.
FICI = the combined effects of the antibiotics and essential oils were calculated and expressed in terms of FIC (FICI= 0.5, synergistic; FICI > 0.5-4.0, no interaction; FICI > 4.0 antagonism).