Part Used : ไม่ระบุ
Activity : DRUG INTERACTION
Solvent/Active Compound :
Type of experiment : in vivo
Type of animal : other
N(Total) : -
N(Treatment) : -
Route : Non-specified
Dose/Conc.(herb) : -
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : Phenelzine
Dose/Conc.(drug) : -
Remark : Suspected potentiation of phenelzine and nifedipine (a CYP3A4 substrate) in animal study. Enzyme-selective effects on other CYP's depend on nature of extract. Ginsenosides inhibit P-gp at high concentrations. Avoid with MAOl's, nifedipine, and in cancer chemotherapy. P. quinquefolius reduced effects of warfarin in healthy volunteers, but P. ginseng had no effect.
Note : Data from review, data incomplete.