Part Used : ไม่ระบุ
Activity : ANTIHYPERGLYCEMIC ACTIVITY
Solvent/Active Compound : saponins
Type of experiment : human
Type of animal : -
Type of study : Double-blind trial
N(Total) : 69 (M/F = 38/31)
N(Treatment) : 46 (M/F = 25/21)
Sex : Both sex
Age : 54.8 +/-7.2 years (control = 53.7 +/-6.8 years)
Route : Oral administration
Dose/Conc.(herb) : 6 capsules each time and thrice a day after meals
Duration : 12 weeks
Type of interaction : Pharmacodynamics
Interaction with drug : Sulfonylurea
Dose/Conc.(drug) : -
Remark : Results: The combined therapy of TFGs with sulfonylureas hypoglycemic drug could lower the blood glucose level and ameliorate clinical symptoms in the treatment of T2DM, and the therapy was relatively safe.
Note : Subject total: patients with type 2 diabetes mellitus (T2DM) not well controlled by sulfonylureas alone were randomly assigned to the treated group (46 cases) and the control group (23 cases).
Dose: Trigonella foenum-graecum L. total saponins (TFGs) capsules; 0.35 g/pill, each gram of powder equals to 16 g of crude drug.